An equimolar pool of all libraries was then prepared for shotgun sequencing on Illumina Hiseq4000 platform using 75bp single-end reads for screening. Tina Huang, a former engineer at Apple, Google, and Twitter, explains why she started API management startup Transposit. Taiwan Patent Application M401603, filed 11th April . Runtime Collective Limited (trading as Brandwatch). Genetics 203, 881891 (2016). Further north and east, individuals from the Baltics (Baltic HG), Scandinavia (SHG), the Balkans (Iron GatesHG) and Ukraine (Ukraine HG) already carried an Oberkassel/Sidelkino admixed ancestry38,40 before 8ka. Early Alpine occupation backdates westward human migration in Late Glacial Europe. Billed once. Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal. We provide a systematic description of the genomic transformations that hunter-gatherer groups experienced from the early Upper Palaeolithic onwards across western and central Eurasia and how those are possibly linked to cultural and climatic changes. Citing . We then removed samples with less than 0.04X coverage (calculated on the mappable, non-recombining region of the Y chromosome98) to avoid arbitrarily placing low-coverage samples at the root of major haplogroups. 14, evac045 (2022). Note: Content may be edited for style and length. Meet Tina Huang. Natural Language Processing (NLP) is another technique that has a well-deserved position in product development. Individuals at this site might mark one of the last occurrences of such high levels of hunter-gatherer-related ancestries, just centuries before the emerging European Bronze Age. Charlton, S. et al. Remember, its the problem that defines the tools we use! Moreover, none of the Epigravettian-associated individuals have more affinity to southern European than to central-eastern European Gravettian-associated groups, as shown by f4(Mbuti, Epigravettian-associated individual/group; Vstonice, Paglicci 12) that is consistent with 0 (Supplementary Data 2.G). USA 111, 22292234 (2014). K.H. 724703 and no. This means you will have no set time limit for completing any of the modules or assignments. Hajdinjak, M. et al. Sign In Create Free Account. In this study, we analyse 356 ancient hunter-gatherer genomes including new genomic data of 116 individuals dated to 355ka alongside a novel contamination-estimation method based on runs of homozygosity. The long-lasting genetic continuity in Iberia is also reflected in the preservation until the Mesolithic of Y-chromosome haplogroup C, which was predominant in pre-LGM groups but rarely found after the LGM in other parts of Europe (Extended Data Figs. H. Rougier and I.C. A. Stoessel performed CT scanning and advised on sampling strategy. Mid and Late Upper Palaeolithic in the Adriatic Basin: chronology, transitions and human adaptations to a changing landscape. In conclusion, our study reveals that western and southwestern Europe served as climatic refugia for the persistence of human groups during the coldest phase of the last Ice Age whereas populations in the Italian peninsula and the eastern European plain were genetically overturned, challenging the role of these regions as glacial refugia for humans. H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. Ideally, we also want lots of data because this will give us more confidence in our results. The three squares highlight Baltic HG groups associated with the Comb Ceramic Culture (CCC) that show a marked increase in Sidelkino-related ancestrycompared to olderBaltic HG groups. Taipei, Taiwan . Tina is a computer science student at Stanford University. A series of f4-symmetry statistics confirm that all the Epigravettian-associated individuals are cladal, and do not share excess affinity with any local (Paglicci 12) or non-local preceding ancestries (Goyet Q116-1, Kostenki 14, Malta 1 or Vstonice) (Supplementary Data 2.F). ADS There is no biographical data to display. She graduated with a degree in Computer Science and Applied Math. The Roger Rabbit's Trousers (1990 film) Credits | JH Movie Collection Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. View Tina_Huang_Resume_i.pdf from HCI 445 at DePaul University. PubMed Central Join now Sign in . Article Wood, R. E. et al. We use cookies to improve your experience and give you personalized content. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in 1 MtDNA and Y-chromosome phylogenies. Graduate - February 2015 to September 2015. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Theyre both important sub-tasks for data scientists to master, but big data data warehousing and data science are only two components of the larger data science endeavor. 9). Fog computing is a computing structure which is distributed in nature. When expanded it provides a list of search options that will switch the search inputs to match the current selection. In addition to her data science work, Tina has also created the popular popular game Code Wars. The f3-statistics were calculated with qp3Pop 435 in ADMIXTOOLS 5.1 package103. In it, we laugh while discussing how to get started in data science and her learning/productivity tricks.Tina: Creates YouTube videos with millions of views on data science careers, learning to code, SQL, productivity, and study techniques. Is a data scientist at one of the world's largest tech companies (she keeps the firm anonymous so she can publish more freely). Previously worked at Goldman Sachs and the Ontario Institute for Cancer Research. Holds a Masters in Computer and Information Technology from the University of Pennsylvania and a bachelors in Pharmacology from the University of TorontoIn this episode, Tina details: Her guidance for preparing for a career in data science from scratch. Her five steps for consistently doing anything. Her strategies for learning effectively and efficiently. What the day-to-day is like for a data scientist at one of the worlds largest tech companies. The software languages she uses regularly. Her SQL course. How her science and computer science backgrounds help her as a data scientist today.Todays episode should be appealing to a broad audience, whether youre thinking of getting started in data science, are already an experienced data scientist, or youre more generally keen to pick up career and productivity tips from a light-hearted conversation.Thanks to Serg Mass, Brindha Ganesan and Ken Jee for providing questions for Tina in Ken's case, a very silly question indeed.The SuperDataScience show's available on all major podcasting platforms, YouTube, and at SuperDataScience.com. Curr. is also supported by the Deutsche Forschungsgemeinschaft (DFG FOR 2237). Los Angeles, California, United States. I admit, i was too confident in my SQL, however that changed after seeing the interview questions that could be asked from different angle, the most important thing i have learnt in this course is CTE, and her Sunday SQL videos on YouTube is icing on cake. 2 The distribution of mtDNA and Y-chromosome haplogroups among different hunter-gatherer groups. Xiamen Guansheng Precision Machinery Co Ltd is a company integrating R&D, production and sales. ISSN 1476-4687 (online) We also compared its affinity to El Mirn (northern Spain), the oldest Magdalenian-associated individual sequenced to date (19ka). 6). This genetic signature is shared among individuals associated with the archaeologically defined Gravettian culture (3326ka) in central and southern Europe and seemingly disappeared after the Last Glacial Maximum4 (LGM). Fu, Q. et al. Track your course progress, set daily goals, and make success a routine. After 7.5ka, as ANF ancestry had reached regions north of the Alps, individuals carrying a hunter-gatherer genetic profile were primarily restricted to the northern fringes of Europe (Fig. In particular, the model achieves 96.21% for the validation and 96.47% for testing using the news aggregator data. Thats exactly why choosing the right feature to build is so important! Freshwater radiocarbon reservoir effects at the burial ground of Minino, Northwest Russia. Sci. Tina teaches SQL in data science in addition to this basic material. Tina Huang Fans Also Viewed . Jan 2022 - Jun 20226 months. Our limited-time offer covers individual course purchases only. We built a Maximum Parsimony tree with 103 mtDNA sequences plus an African sequence as the outgroup (not shown) after the removal of individuals younger than 6.5ka and mtDNAs from the same site with an identical placement. Details are provided in Data S2.B. USA 117, 1279112798 (2020). A Passive Flier. & Hlie, J. F. Temperature and precipitation regime in LGM human refugia of southwestern Europe inferred from 13C and 18O of large mammal remains. Were dedicated to providing you the best ofNews, with a focus on dependability andBusiness. (eds. & Nielsen, R. ANGSD: analysis of next generation sequencing data. Check out my courses where we apply scientifically backed learning techniques to accomplish our goals. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. Tina is excellent when it comes to getting overall data science career advice. Previous studies identified two different genetic compositions in Magdalenian-associated individualsthe GoyetQ2 cluster including central-western European genomes dated to around 15ka (from France, Belgium and Germany), and the ancestry of the El Mirn individual from Spain4,14 from around 19ka. About the Instructor. Ecol. The Sidelkino ancestry also emerged around 14ka with its first direct evidence in eastern Europe43 dated to 13ka. Evol. These authors contributed equally: Cosimo Posth, He Yu, Archaeo- and Palaeogenetics, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tbingen, Tbingen, Germany, Cosimo Posth,Dorothe G. Drucker,Herv Bocherens,Christoph Wiing,Nicholas J. Conard&Katerina Harvati, Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, Cosimo Posth,He Yu,Ayshin Ghalichi,Hlne Rougier,Yilei Huang,Harald Ringbauer,Adam B. Rohrlach,Kathrin Ngele,Vanessa Villalba-Mouco,Rita Radzeviciute,Tiago Ferraz,Alexander Stoessel,Rezeda Tukhbatova,Wolfgang Haak&Johannes Krause, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China, Department of Anthropology, California State University Northridge, Northridge, CA, USA, Universit de Bordeaux, CNRS, MC, PACEA UMR 5199, Pessac, France, Isabelle Crevecoeur,Andr Morala,Stphane Madelaine,Priscilla Bayle,Bruno Maureille,Jean-Guillaume Bordes&Mona Le Luyer, School of Mathematical Sciences, University of Adelaide, Adelaide, South Australia, Australia, Instituto Universitario de Investigacin en Ciencias Ambientales de Aragn, IUCA-Aragosaurus, Zaragoza, Spain, Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany, Institute of Zoology and Evolutionary Research, University of Jena, Jena, Germany, Center of Excellence Archaeometry, Kazan Federal University, Kazan, Russia, Department of Biology, University of Florence, Florence, Italy, Martina Lari,Alessandra Modi&Stefania Vai, Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia, Tina Saupe,Christiana L. Scheib&Luca Pagani, St Johns College, University of Cambridge, Cambridge, UK, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy, Department of Biology, University of Padova, Padova, Italy, Department of Chemistry G. Ciamician, Alma Mater Studiorum, University of Bologna, Bologna, Italy, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, UMR 8068 CNRS, TEMPSTechnologie et Ethnologie des Mondes Prhistoriques, Nanterre Cedex, France, Laurent Klaric,Olivier Bignon-Lau,Grgory Debout,Michel Orliac,Pierre Bodu,Bndicte Souffi&Frdrique Valentin, Muse National de Prhistoire, Les Eyzies de Tayac, France, UMR 5140 CNRS, Archologie des Socits Mditerranennes, Universit Paul-Valry, Montpellier, France, UMR 7194, Histoire Naturelle de lHomme Prhistorique (HNHP), Dpartement Homme et Environnement, Musum National dHistoire Naturelle, CNRS, UPVD, Paris, France, Association APRAGE (Approches pluridisciplinaires de recherche archologique du Grand-Est), Besanon, France, Skeletal Biology Research Centre, School of Anthropology and Conservation, University of Kent, Canterbury, UK, Dipartimento di Scienze Fisiche, della Terra e dellAmbiente, U.R. Opin. Curr. Her YouTube channel advises data science jobs, self-study, boosting productivity, resume reviews, etc. Here, we report genomic data from 4 individuals, including 3 approximately 13,000-year-old genomes from northeastern Italy (Pradis 1), northwestern Italy (Arene Candide 16) and Sicily (San Teodoro 2), as well as increased genome-wide coverage from Tagliente 215 dated to 17ka. It just raised $12.2 million. 2932 and Supplementary Table 4). First up is the MIT researcher and YouTuber Jordan Harrod. 35, 15471549 (2018).