Timing is everything with respect to outcomes. Government agencies are ignoring the science. In November, CETF gave the group an additional $500,000 for a phase 3 clinical trial that might show conclusive proof of efficacy. They all promised me when fluvoxamine passed Phase 3 trials, nearly everyone would use it. This is what the Seftel trial at Golden Gate fields used. Instead, it erodes confidence in our government to provide timely advice that is in the public interest. May 16, 2022. Dosage there is 30mg once a day. Saving the world has been a theme of Kirschs life for years. The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). After boosting unproven covid drugs and campaigning against vaccines, Steve Kirsch was abandoned by his team of scientific advisersand left out of a job. They never make things worse so are safe to try. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. It's hard to ignore this lecture in explaining why the drug is so effective. Where did it go wrong. Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. After one or two conversations like that, I got tired of arguing, so I started avoiding his calls, she said. YouTube , , , fluvoxamine, , , , , , , , , , Fluvoxamine, created 37 years ago, is an inexpensive and widely available generic drug. Im just telling you the truth. Fluvoxamine has a systematic review and meta-analysis published in a top medical journal. Online Status. 47).. . The antidepressant fluvoxamine, which is generic, but sometimes sold under the brand name Luvox, is a member of the class of drugs known as selective serotonin reuptake inhibitors (SSRIs). We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. The NIH Guidelines committee is being very slow to react (we have no idea if they are even considering the drug because nobody is allowed to know that because all their deliberations are kept secret). He is the inventor of the optical mouse and one of the first Internet search engines, Infoseek. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. Added to FLCCC protocols and Fareed-Tyson protocol among others. Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. By Steve Kirsch Mar 14, 2021 Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for a single drug to be 100% successful. Please, As of November 13, fluvoxamine has been proven to work in every trial that has published results, including, studies. As of November 13, fluvoxamine has been proven to work in every trial that has published results, including outpatient and inpatient studies. The rest of the board soon followed. Keyword: ivermectin The US government accused Janssen of improperly promoting the antipsychotic drug Risperdal to dementia patients despite the drug increasing deaths in the elderly. While Kirsch had the final say in who received grants, no one I spoke with expressed concerns about what projects had been funded, or why. One of the first CETF grants was to investigate the antimalarial hydroxychloroquine. Paper reviewing the evidence and mechanisms of action for fluvoxamine: Lenze Phase 2 RCT published Nov 12, 2020: Seftel RWE trial that confirmed the Phase 2 trial published Feb 1, 2021. Should you get vaccinated? Steve Kirsch | TrialSite News But the potential upsides. Fluvoxamine for COVID: what you need to know - Substack His appearance on an episode of anti-covid-vaccine, pro-ivermectin pundit Bret Weinsteins DarkHorse podcast, alongside Robert Malone, a prominent source of vaccine misinformation, introduced Kirsch to followers of the intellectual dark web, who have since embraced him as a fellow truth-teller. You can use fluoxetine as well (aka Prozac). Andrew Wakefield after 25 years: Paving the way for COVID-19 quacks and With covid, 80% of your patient population does just peachy with no treatment at all, just a little bed rest and fluid. It is perhaps the greatest unnecessary loss of life in American history. Dr. Seftel is an NIH-funded researcher and an NIH reviewer. Completely avoid caffeine, alcohol, tylenol, and benadryl. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. Steve Kirsch: $25,000 to Anyone that Proves Fluvoxamine - TrialSiteNews Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. I couldnt tell I was on the drug. These huge businesses do often prioritize profits over human health: in 2009, Pfizer paid a $2.3 billion settlement over kickbacks and fraudulent marketing, including a $1.3 billion felony fine. Most recent articles first. Do the NIH and WHO COVID treatment recommendations need to be fixed? I mean, he really, truly has a heart of gold, Char told me. Hes very convincing. This post was written to memorialize the corruption. . Several former members told me he began relentlessly pressuring them to promote the drug in media stories, often during exhausting, circuitous conversations. Expect similar things to happen when Eiger applies for an EUA for interferon lambda, a drug with a 89% efficacy in phase 3 trials. Physicians who use the drug for COVID now swear by it. PDF Fluvoxamine - The backstory But they dont want their names used. Don't underestimate the virus. Or just depression about the vaccine mandates? It doesnt get any better than this. In the early days of the pandemic, as billions of dollars poured into the hunt for novel treatments and vaccines, veteran Silicon Valley entrepreneur Steve Kirsch did what hes always done: He went looking for an underdog. In three phone conversations, as well as dozens of emails, his responses to questions about claims in this story were imprecise or constantly changing. Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. We could have saved a lot of lives. Those who know Kirsch say this is a typical tactic. The evidence is solid. If you take fluvoxamine, please avoid caffeine while on the drug. Tech Entrepreneur Crusades for SSRI as COVID Therapy You can experience serious side effects if you do not pay attention to interactions such as if you are currently on another SSRI of a different type. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. The drug was FDA-approved more than 65 years ago. But they will refuse to give it to you even after being proven in a Phase 3 trial that was approved by the WHO. has tons of info on fluvoxamine with all the links. - Quora, Heres presentation I gave at the re-open California Conference on January 9,2021: How to fix the problemHow to fix the problem Steve Kirsch Executive DirectorCOVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008Google Docs[https://docs.google.com/presentation/d/1-A4y78wv3tTPmVu57FOabY6j-MJbPwMGojKwZfaCkAs/. Los Altos Hills resident touts fluvoxamine as COVID-19 treatment I couldn't agree more. If not, they should at least acknowledge that fluvoxamine might be helpful by at least listing it as a possibility. Here's why. Reason is the hospital gets release from liability if they follow NIH guidelines. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to completely avoid the list in the previous paragraph, or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). You can help by bringing this document to your doctor's attention. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Once the Phase 2 result came out, it should have been embraced by doctors. You will be wired for 24 hours if you dont heed my advice. By Steve Kirsch Last updated: March 14, 2021 After I appeared on the60 Mi nut es story about fluvoxamine,I've received a lot of questions from people about how to treat COVID. This is why Cliff doesnt talk to me. P-value was 10^-14 on that study (done by Dr. All the supporting observational studies were positive as well. After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. We didnt come up with better mouse technology than Microsoft did. The anecdotal data of 100% success rates is further icing on the cake. Is fluvoxamine helpful for patients with the coronavirus? Is it - Quora The web value rate of skirsch.io is 2 . Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. Have the drug on hand. Last Checked: 03/03/2023. Incriminating evidence - Steve Kirsch's newsletter - Substack Thats what creates some of these heroes.. If you take fluvoxamine, please avoid caffeine while on the drug. In 2013, Johnson & Johnson paid $2.2 billion for its own kickback and fraud scandal, including a specific $400 million fine for its subsidiary Janssen, which manufactures the covid vaccine. Design thinking was supposed to fix the world. Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008 Google Docs This is a more comprehensive look at the key evidence supporting fluvoxamine: Fluvoxamine for COVID-19 (One of them, Eric Lenze, was in fact giving a presentation on fluvoxamine to the National Institutes of Health the next day.) just like ivermectin). Steve Kirsch cut the check, which allowed Dr. Lenze to finish recruiting the 152 patients he needed for his trial. So you can address your OCD and if you get COVID, youll can up the dose. Please. Its a cycle that feeds mistrust and boosts the profiles of influencers who present themselves in opposition to official authorities. This looks ominous, but it harmless. That was a lie. Fluvoxamine public data repository: The fluvoxamine public repository has all the documents related to fluvoxamine for COVID, including the RCT, RWE, observational studies and a link to the 1 hour lecture on serotonin and fluvoxamine. Steve Kirsch Home page Doctors who have used fluvoxamine in the US and other countries swear by it. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Patients should be advised to limit/avoid the use of caffeine while on the drug since fluvoxamine extends the half life of caffeine (making you super wired). Substitutions. All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. 33. Dr. Eric Lenze: So the results were really pretty. The track management was so impressed, they asked for prescriptions. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. They were giving covid patients the antidepressant fluvoxamine as soon as possible after diagnosis, based on anecdotes about the drug limiting the runaway immune response that causes many severe symptoms. If there is a better drug on the table today than fluvoxamine, the NIH panel should put that one on the guidelines. Ive used it personally at 50mg twice a day and experience no adverse events at all. Enter the email address you signed up with and we'll email you a reset link. Keyword: mit BOMBSHELL: Top biostats professor admits we have NO CLUE # of people KILLED by COVID vaccines, he wrote. One is to reduce the threat of nuclear war. For example, tylenol+caffeine+fluvoxamine can lead to serotonin syndrome. So when a group of scientists applied for an EUA for fluvoxamine, what did the FDA do? That was a big mistake because the original paper contained text related to earlier studies and the editors chopped it out. Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. 95% confidence effect size is 75% or more. But the whole process has gone too slowly for Kirsch. Less than a week later, David Seftel read about the Lenze trial, and ignored the JAMA advice. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. Their willingness to lie did. With cases spiking, the Los Angeles area banned gatherings. It doesnt get much better than that. In May, all 12 members of CETFs scientific advisory board resigned, citing his alarming dangerous claims and erratic behavior. Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. His latest startup, M10, is a spin-off of a spin-off that sells a blockchain for banks. In some cases, youd want to taper down the dosage. If you start later, doctors use higher dosages and compliance becomes a bigger problem. Some people are jittery, but usually that is because the doctor either prescribed a dosage higher than 50mg twice a day or didnt notify the patient to. NIH is still unsure whether fluvoxamine should be used to treat COVID. just like ivermectin). Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. My experience is very typical. Thats pretty typical, but your mileage may vary. Here are my answers. Doctors who are most familiar with the drug would prescribe it to their patients. As of January 18, 2021, the CDC estimates that 90,000 Americans will die from COVID in just the next 3 weeks. Sage Hana. Fluvoxamine - The backstory T he i nsi de st ory behi nd how f l uvoxami ne became a CO V I D t herapy By Steve Kirsch Last updated: June 3, 2021 . Every year, we pick the 10 technologies that matter the most right now. Long haul. Added to FLCCC protocols and Fareed-Tyson protocol among others. Why the FDA should grant an EUA for fluvoxamine immediately, Links to evidence about fluvoxamine including the public data repository, Here's the first one: The effect size is huge if the drug is given early right after symptoms start. (article I did after the TOGETHER trial). Steve Kirsch reported that doctors commonly say (of fluvoxamine), "This is the most powerful drug in my arsenal. We need to keep people out of the hospital in the first place. You will be wired for 24 hours if you dont heed my advice. Fluvoxamine, Proxalutamide, and Ivermectin: 100% success Peter Meinke, another former board member, spent nearly three decades in drug discovery at Merck. At the end of May this year, Siliciano emailed the other advisors to say that Kirsch had gone off the deep end and he was cutting ties. People who report not tolerating the drug are typically prescribed too high a dose. Di scl ai mer: T he vi ews expressed i n t hi s art i cl e are my own personal opi ni on based on my 1, 000+ hour st udy of cut t i ng edge . To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here. Steve Kirsch is baffled. Dr. Joe Ladapo wrote a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients." Yes, these were successes, but the successes could have been bigger if we had really paid attention to marketing. 4000fluvoxamine750 The board members I spoke to say they refused to publicly promote any drugs for off-label use and tried to explain to Kirsch that its incredibly common for exciting results from small trials to disappear in larger ones. But as Kirsch has clashed with the experts he initially surrounded himself with, hes grown increasingly close to others who share his perspectives on vaccineswho have, in turn, provided a large and receptive audience to his claims about a fluvoxamine conspiracy. About - vacsafety.org There were no studies reported out so far where fluvoxamine made things worse or neutral. In September, he resigned as CEO and gave up his board seat. Steve Kirsch is looking for an explanation for 171,000 excess deaths. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). 1 hr ago. Food/drugs to avoid while on fluvoxamine. See this Wall Street Journal op-ed. Why the FDA should grant an EUA for fluvoxamine immediately, a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Your best bet is to. CETF Founder Steve Kirsch discusses why we can't wait for a COVID-19 vaccine, the importance of researching existing drugs now, and our work to raise funds for outpatient trials to identify effective . Online. Medicine today isnt about saving your life. Steve Kirsch is a Silicon Valley philanthropist. None of this would really matter if Kirschs views on vaccinations were private, or shared with a limited audience. Silence from the medical community. Steve Kirsch. In the studies and the anecdotes I am aware of, everyone reversed symptoms within days of getting the drug. Its sad, but its true, he told me. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. If you continue to get this message, Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. skirsch.io Steve Kirsch Home page